IN VITRO PHARMACOLOGICAL SCREENING METHODS FOR ANTI-INFLAMMATORY AGENTS
نویسندگان
چکیده
منابع مشابه
Development and use a Novel Combined In-vivo and In-vitro Assay for Anti-inflammatory and Immunosuppressive Agents
Contact hypersensitivity (CHS) mouse model induced by 2, 4-dinitrofluorobenzene (DNFB) is thought to be a T helper 1 (Th1)-dominant response and used for investigating anti-inflammatory and immunosuppressive agents. However, it is hardly used for screening large-scale drugs because of the large number of animals and complex mechanisms involved in-vivo. In this study, we focused on whether T lym...
متن کاملDevelopment and use a Novel Combined In-vivo and In-vitro Assay for Anti-inflammatory and Immunosuppressive Agents
Contact hypersensitivity (CHS) mouse model induced by 2, 4-dinitrofluorobenzene (DNFB) is thought to be a T helper 1 (Th1)-dominant response and used for investigating anti-inflammatory and immunosuppressive agents. However, it is hardly used for screening large-scale drugs because of the large number of animals and complex mechanisms involved in-vivo. In this study, we focused on whether T lym...
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Thrombolytic therapy and mechanical interventions are frequently used in the treatment of thrombotic diseases. The basic problems with current thrombolytic therapy include slow and incomplete thrombolysis and frequent bleeding complications. Therefore, there is a need of continuity to develop & screen out the various natural agents that possess antithrombotic activity by using different screeni...
متن کاملNew anti-inflammatory agents.
The pyrrole derivatives la, b and 2a, b were used as precursors for the preparation of N-substituted pyrrole derivatives 3a, b-9a, b and pyrrolo[2,3-d]pyrimidines 13-16. Also, all the newly prepared products were tested for anti-inflammatory activity as analogues to fenamates, and some of them revealed moderate anti-inflammatory activity compared to the standard drug indomethacin.
متن کاملdevelopment and use a novel combined in-vivo and in-vitro assay for anti-inflammatory and immunosuppressive agents
contact hypersensitivity (chs) mouse model induced by 2, 4-dinitrofluorobenzene (dnfb) is thought to be a t helper 1 (th1)-dominant response and used for investigating anti-inflammatory and immunosuppressive agents. however, it is hardly used for screening large-scale drugs because of the large number of animals and complex mechanisms involved in-vivo. in this study, we focused on whether t lym...
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ژورنال
عنوان ژورنال: Asian Journal of Pharmaceutical and Clinical Research
سال: 2018
ISSN: 2455-3891,0974-2441
DOI: 10.22159/ajpcr.2018.v11s4.31709